Gene Flow and Individual Relatedness Suggest Population Spatial Connectivity

Gene Flow and Individual Relatedness Suggest Population Spatial Connectivity

Gene Movement and Particular person Relatedness Counsel Inhabitants Spatial Connectivity of Sinogastromyzon sichangensis (Cypriniformes: Balitoridae) within the Chishui River, China

  • Sinogastromyzon sichangensisis a hillstream loach endemic to the higher Yangtze River, China. It’s unclear whether or not this fish lives in a really restricted space or could also be dispersed over a protracted distance. Within the current research spatial connectivity of populations of  sichangensis was investigated primarily based on 343 people collected from 12 websites of Chishui River and using 22 microsatellite loci.
  • The outcomes of genetic variety evaluation confirmed that noticed heterozygosity (HO) and polymorphism data content material (PIC) ranged from 0.5653 to 0.6999 and 0.8513 to 0.8819, respectively. Inhabitants construction evaluation advised that  sichangensishad an unclear genetic construction.
  • AMOVA confirmed that 69.36% of genetic variation was attributed to differentiation inside people and all of the pairwise genetic differentiation indices (FST) had been low (imply FST = 0.0344), indicating weak differentiation amongst these populations.
  • Estimation of gene circulate confirmed frequent circulate amongst populations, and up to date ranges (imply up to date migration fee, mc= 0.0131) had been roughly equal to historic ranges (imply historic migration fee, mh = 0.0147).
  • Particular person relatedness evaluation revealed a excessive stage of sibship inside and amongst completely different populations. The frequent gene circulate and widespread sibship had been on account of  sichangensislaying drifting eggs which journey for a protracted distance till hatching, after which the juveniles or adults migrate upstream.
  • The outcomes of unclear geographic construction and frequent alternate additionally point out that it’s essential to lower the unfavourable impacts of anthropogenic actions on the connectivity of rivers to guard the migration routes of S. sichangensis.
geknome
geknome

Human Protein ECT2, ECT2 ELISA KIT

ELI-09348h 96 Tests
EUR 824

ECT2 siRNA

20-abx914934
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

ECT2 siRNA

20-abx914935
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

ECT2 Peptide

45-517P 0.1 mg
EUR 338
Description: ECT2 Peptide

ECT2 Antibody, HRP conjugated

1-CSB-PA888001LB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

ECT2 Antibody, FITC conjugated

1-CSB-PA888001LC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

ECT2 Antibody, Biotin conjugated

1-CSB-PA888001LD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

ECT2 Blocking Peptide

33R-7035 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ECT2 antibody, catalog no. 70R-5730

ECT2 Blocking Peptide

33R-4471 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ECT2 antibody, catalog no. 70R-5714

pCMV-SPORT6-ECT2

PVT12957 2 ug
EUR 391

Anti-Phospho-ECT2 T790 Antibody

P01862 100ug
EUR 432
Description: Rabbit Polyclonal Phospho-ECT2 T790 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Polyclonal Goat Anti-ECT2 Antibody

APG00096G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-ECT2 . This antibody is tested and proven to work in the following applications:

Monoclonal ECT2 Antibody, Clone: 1691CT516.3.3

AMM02569G 0.1ml
EUR 484
Description: A Monoclonal antibody against Human ECT2. The antibodies are raised in Mouse and are from clone 1691CT516.3.3. This antibody is applicable in WB, E

Mouse ECT2 shRNA Plasmid

20-abx970099
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Human ECT2 shRNA Plasmid

20-abx951320
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Monoclonal ECT2 monoclonal antibody (M01), Clone: 5D4

AMM04340G 0.1mg
EUR 484
Description: A Monoclonal antibody against Human ECT2 monoclonal (M01). The antibodies are raised in mouse and are from clone 5D4. This antibody is applicable in WB

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx104055
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx104056
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx028279-400ul 400 ul
EUR 523

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx028279-80l 80 µl
EUR 286

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx432637-200ul 200 ul
EUR 384

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx334431
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ect2 ORF Vector (Mouse) (pORF)

ORF043598 1.0 ug DNA
EUR 506

Ect2 ORF Vector (Mouse) (pORF)

ORF043599 1.0 ug DNA
EUR 506

Ect2 ORF Vector (Mouse) (pORF)

ORF043600 1.0 ug DNA
EUR 506

ECT2 ORF Vector (Human) (pORF)

ORF018676 1.0 ug DNA
EUR 405

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (HRP)

20-abx337249
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (FITC)

20-abx337250
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

20-abx337251
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

20-abx272498
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

ECT2 sgRNA CRISPR Lentivector set (Human)

K0652601 3 x 1.0 ug
EUR 339

Ect2 sgRNA CRISPR Lentivector set (Mouse)

K4451601 3 x 1.0 ug
EUR 339

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human)

4-PAC451Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2)

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human)

4-PAC451Hu02
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2)

Recombinant Epithelial Cell Transforming Sequence 2 (ECT2)

4-RPC451Hu01
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Epithelial Cell Transforming Sequence 2 expressed in: E.coli

Recombinant Epithelial Cell Transforming Sequence 2 (ECT2)

4-RPC451Hu02
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Epithelial Cell Transforming Sequence 2 expressed in: E.coli

Recombinant Epithelial Cell Transforming Sequence 2 (ECT2)

4-RPC451Mu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Epithelial Cell Transforming Sequence 2 expressed in: E.coli

ECT2 sgRNA CRISPR Lentivector (Human) (Target 1)

K0652602 1.0 ug DNA
EUR 154

ECT2 sgRNA CRISPR Lentivector (Human) (Target 2)

K0652603 1.0 ug DNA
EUR 154

ECT2 sgRNA CRISPR Lentivector (Human) (Target 3)

K0652604 1.0 ug DNA
EUR 154

Ect2 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4451602 1.0 ug DNA
EUR 154

Ect2 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4451603 1.0 ug DNA
EUR 154

Ect2 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4451604 1.0 ug DNA
EUR 154

Ect2 3'UTR Luciferase Stable Cell Line

TU105588 1.0 ml Ask for price

ECT2 Protein Vector (Human) (pPB-C-His)

PV074701 500 ng
EUR 552

ECT2 Protein Vector (Human) (pPB-N-His)

PV074702 500 ng
EUR 552

ECT2 Protein Vector (Human) (pPM-C-HA)

PV074703 500 ng
EUR 552

ECT2 Protein Vector (Human) (pPM-C-His)

PV074704 500 ng
EUR 552

ECT2 Protein Vector (Mouse) (pPB-C-His)

PV174390 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPB-N-His)

PV174391 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-HA)

PV174392 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-His)

PV174393 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPB-C-His)

PV174394 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPB-N-His)

PV174395 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-HA)

PV174396 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-His)

PV174397 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPB-C-His)

PV174398 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPB-N-His)

PV174399 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-HA)

PV174400 500 ng
EUR 1065

ECT2 Protein Vector (Mouse) (pPM-C-His)

PV174401 500 ng
EUR 1065

ECT2 3'UTR GFP Stable Cell Line

TU056547 1.0 ml
EUR 2333

ECT2 3'UTR Luciferase Stable Cell Line

TU006547 1.0 ml
EUR 2333

Ect2 3'UTR GFP Stable Cell Line

TU155588 1.0 ml Ask for price

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC

4-PAC451Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Biotinylated

4-PAC451Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Biotin.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Cy3

4-PAC451Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Cy3.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), FITC

4-PAC451Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with FITC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), HRP

4-PAC451Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with HRP.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), PE

4-PAC451Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with PE.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC

4-PAC451Hu02-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Biotinylated

4-PAC451Hu02-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Biotin.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Cy3

4-PAC451Hu02-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Cy3.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), FITC

4-PAC451Hu02-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with FITC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), HRP

4-PAC451Hu02-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with HRP.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), PE

4-PAC451Hu02-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with PE.

Mouse Epithelial Cell Transforming Sequence 2 (ECT2) Protein

20-abx650860
  • EUR 676.00
  • EUR 286.00
  • EUR 2082.00
  • EUR 801.00
  • EUR 481.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Epithelial Cell Transforming Sequence 2 (ECT2) Protein

20-abx066450
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Epithelial Cell Transforming Sequence 2 (ECT2) Protein

20-abx066451
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC-Cy7

4-PAC451Hu01-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC-Cy7.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC-Cy7

4-PAC451Hu02-APC-Cy7
  • EUR 571.00
  • EUR 6430.00
  • EUR 1705.00
  • EUR 760.00
  • EUR 319.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC-Cy7.

ECT2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0652605 3 x 1.0 ug
EUR 376

Ect2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4451605 3 x 1.0 ug
EUR 376

ECT2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0652606 1.0 ug DNA
EUR 167

ECT2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0652607 1.0 ug DNA
EUR 167

ECT2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0652608 1.0 ug DNA
EUR 167

Ect2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4451606 1.0 ug DNA
EUR 167

Ect2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4451607 1.0 ug DNA
EUR 167

Ect2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4451608 1.0 ug DNA
EUR 167

CD11b Antibody Antibody

ABD2911 100 ug
EUR 438

H2B Antibody Antibody

AF4659 200ul
EUR 376
Description: H2B Antibody Antibody detects endogenous levels of H2B.

anti- Antibody^Polyclonal antibody control antibody

LSMab09882 100 ug
EUR 438

Antibody

A1360-500 Ask for price

Anti-Anti-SEPT2 Antibody antibody

STJ25475 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ25477 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-SEPT8 Antibody antibody

STJ25479 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT2 Antibody antibody

STJ28365 100 µl
EUR 277

Anti-Anti-SEPT7 Antibody antibody

STJ28963 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT8 Antibody antibody

STJ117206 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-SEPT12 Antibody antibody

STJ117759 100 µl
EUR 277
Description: This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

Anti-Anti-MARCH6 Antibody antibody

STJ118549 100 µl
EUR 277

Anti-Anti-MARCH6 Antibody antibody

STJ118550 100 µl
EUR 277

Anti-Anti-MARCH7 Antibody antibody

STJ118752 100 µl
EUR 277

Anti-Anti-SEPT3 Antibody antibody

STJ118990 100 µl
EUR 277

Anti-Anti-SEPT1 antibody antibody

STJ119580 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

Anti-Anti-SEPT7 Antibody antibody

STJ116214 100 µl
EUR 277
Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Anti-Anti-SEPT6 antibody antibody

STJ11100949 100 µl
EUR 277
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Anti-Anti-SEPT9 Antibody antibody

STJ111369 100 µl
EUR 277
Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.

Anti-Anti-SEPT11 Antibody antibody

STJ111530 100 µl
EUR 277

Anti-Anti-SEPT4 Antibody antibody

STJ112276 100 µl
EUR 277
Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.

Anti-Anti-MARCH9 Antibody antibody

STJ112609 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ113941 100 µl
EUR 277

Anti-Anti-SEPT11 Antibody antibody

STJ114081 100 µl
EUR 277

Anti-Anti-SEPT5 Antibody antibody

STJ114819 100 µl
EUR 277
Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

Anti-Anti-MARCH8 Antibody antibody

STJ114828 100 µl
EUR 277

Ly1 Antibody Reactive (LYAR) Antibody

20-abx123734
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319900
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319901
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319905
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycoprotein Antibody (GP) Antibody

20-abx319913
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ly1 Antibody Reactive (LYAR) Antibody

20-abx311665
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Anti-Glycolipid Antibody (AGA) Antibody

20-abx004855
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Anti-Glycolipid Antibody (AGA) Antibody

abx036399-100ug 100 ug
EUR 391

Ly1 Antibody Reactive (LYAR) Antibody

20-abx008109
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Ly1 Antibody Reactive (LYAR) Antibody

20-abx014333
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-400ul 400 ul
EUR 523

Ly1 Antibody Reactive (LYAR) Antibody

abx033330-80l 80 µl
EUR 286

Ly1 Antibody Reactive (LYAR) Antibody

abx234901-100ug 100 ug
EUR 551

Anti-Glycolipid Antibody (AGA) Antibody

abx230204-100ug 100 ug
EUR 481

Ly1 Antibody Reactive (LYAR) Antibody

20-abx324434
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Monoclonal NGF/proNGF Neutralizing Antibody Antibody

AMM06679G 0.05mg
EUR 528
Description: A Monoclonal antibody against Human NGF/proNGF Neutralizing. The antibodies are raised in Mouse. This antibody is applicable in E

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-01mg 0,1 mg
EUR 267.5
Description: anti-CD22 monoclonal antibody

Anti CD22 Antibody: CD22 Monoclonal Antibody

065-A-1000ug 1000 ug
EUR 1282.5
Description: anti-CD22 monoclonal antibody

Anti-IgG1 Negative Control Antibody antibody

STJ16100881 1 mL
EUR 478

Anti-Noelin Antibody BIOTIN Antibody BIOTIN

STJ501938 100 µg
EUR 586

Anti-Noelin Antibody FITC Antibody FITC

STJ501939 100 µg
EUR 586

Anti-Noelin Antibody BIOTIN Antibody BIOTIN

STJ501940 100 µg
EUR 586

Anti-Noelin Antibody FITC Antibody FITC

STJ501941 100 µg
EUR 586

Antibody for Human alpha Tubulin Antibody

SPC-692D 0.1mg
EUR 354
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is unconjugated.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A390 0.1mg
EUR 401
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 390.

Antibody for Human alpha Tubulin Antibody

SPC-692D-A488 0.1mg
EUR 400
Description: A polyclonal antibody for alpha Tubulin from Human. The antibody is produced in rabbit after immunization with human synthetic peptide of Human alpha-Tubulin. The Antibody is tested and validated for WB, ICC/IF assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100). This alpha Tubulin antibody is conjugated to ATTO 488.

Case Report: Identification of a Novel Variant (m.8909T>C) of Human Mitochondrial ATP6 Gene and Its Practical Penalties on Yeast ATP Synthase

 With the arrival of subsequent era sequencing, the record of mitochondrial DNA (mtDNA) mutations recognized in sufferers quickly and constantly expands. They’re regularly present in a restricted quantity of circumstances, typically a single particular person (as with the case herein reported) and in heterogeneous genetic backgrounds (heteroplasmy), which makes it tough to conclude about their pathogenicity and useful penalties.

As an organism amenable to mitochondrial DNA manipulation, capable of survive by fermentation to loss-of-function mtDNA mutations, and the place heteroplasmy is unstable, Saccharomyces cerevisiae is an wonderful mannequin for investigating novel human mtDNA variants, in isolation and in a managed genetic context.

We herein report the identification of a novel variant in mitochondrial ATP6 gene, m.8909T>C. It was discovered together with the well-known pathogenic m.3243A>G mutation in mt-tRNALeu.

We present that an equal of the m.8909T>C mutation compromises yeast adenosine tri-phosphate (ATP) synthase meeting/stability and reduces the speed of mitochondrial ATP synthesis by 20-30% in comparison with wild sort yeast.

Different beforehand reported ATP6 mutations with well-established pathogenicity (like m.8993T>C and m.9176T>C) had been proven to have related results on yeast ATP synthase. It may be inferred that alone the m.8909T>C variant has the potential to compromise human well being.

Investigating the Position of Telomere and Telomerase Related Genes and Proteins in Endometrial Most cancers

  • Endometrial most cancers (EC) is the most typical gynaecological malignancy. Present prognostic markers are insufficient to precisely predict affected person survival, necessitating novel prognostic markers, to enhance remedy methods.
  • Telomerase has a novel function throughout the endometrium, while aberrant telomerase exercise is a trademark of many cancers.
  • The intention of the present in silico research is to research the function of telomere and telomerase related genes and proteins (TTAGPs) in EC to establish potential prognostic markers and therapeutic targets.
  • Evaluation of RNA-seq knowledge from The Most cancers Genome Atlas recognized differentially expressed genes (DEGs) in EC (568 TTAGPs out of 3467) and ascertained DEGs related to histological subtypes, greater grade endometrioid tumours and late stage EC.
  • Practical evaluation demonstrated that DEGs had been predominantly concerned in cell cycle regulation, whereas the survival evaluation recognized 69 DEGs related with prognosis. The protein-protein interplay community constructed facilitated the identification of hub genes, enriched transcription issue binding websites and medicines that will goal the community.
  • Thus, our in silico strategies distinguished many important genes related to telomere upkeep that had been beforehand unknown to contribute to EC carcinogenesis and prognosis, together with NOP56WFS1ANAPC4and TUBB4A. Probing the prognostic and therapeutic utility of those novel TTAGP markers will type an thrilling foundation for future analysis.

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