Gene Flow and Individual Relatedness Suggest Population Spatial Connectivity

Gene Flow and Individual Relatedness Suggest Population Spatial Connectivity

Gene Movement and Particular person Relatedness Counsel Inhabitants Spatial Connectivity of Sinogastromyzon sichangensis (Cypriniformes: Balitoridae) within the Chishui River, China

  • Sinogastromyzon sichangensisis a hillstream loach endemic to the higher Yangtze River, China. It’s unclear whether or not this fish lives in a really restricted space or could also be dispersed over a protracted distance. Within the current research spatial connectivity of populations of  sichangensis was investigated primarily based on 343 people collected from 12 websites of Chishui River and using 22 microsatellite loci.
  • The outcomes of genetic variety evaluation confirmed that noticed heterozygosity (HO) and polymorphism data content material (PIC) ranged from 0.5653 to 0.6999 and 0.8513 to 0.8819, respectively. Inhabitants construction evaluation advised that  sichangensishad an unclear genetic construction.
  • AMOVA confirmed that 69.36% of genetic variation was attributed to differentiation inside people and all of the pairwise genetic differentiation indices (FST) had been low (imply FST = 0.0344), indicating weak differentiation amongst these populations.
  • Estimation of gene circulate confirmed frequent circulate amongst populations, and up to date ranges (imply up to date migration fee, mc= 0.0131) had been roughly equal to historic ranges (imply historic migration fee, mh = 0.0147).
  • Particular person relatedness evaluation revealed a excessive stage of sibship inside and amongst completely different populations. The frequent gene circulate and widespread sibship had been on account of  sichangensislaying drifting eggs which journey for a protracted distance till hatching, after which the juveniles or adults migrate upstream.
  • The outcomes of unclear geographic construction and frequent alternate additionally point out that it’s essential to lower the unfavourable impacts of anthropogenic actions on the connectivity of rivers to guard the migration routes of S. sichangensis.
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ECT2 antibody

70R-5714 50 ug
EUR 467
Description: Rabbit polyclonal ECT2 antibody raised against the middle region of ECT2

ECT2 antibody

70R-5730 50 ug
EUR 467
Description: Rabbit polyclonal ECT2 antibody raised against the middle region of ECT2

ECT2 Antibody

CAC11271-100ug 100ug
EUR 314

ECT2 Antibody

CAC11271-50ug 50ug
EUR 199.2

ECT2 Antibody

1-CSB-PA888001LA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IP:1:200-1:2000

ECT2 Antibody

GWB-MS591F 50ug Ask for price

ECT2 Antibody

GWB-MS592G 50ug Ask for price

ECT2 Conjugated Antibody

C43917 100ul
EUR 476.4

ECT2 Polyclonal Antibody

E-AB-53424-120uL 120uL
EUR 240
Description: Unconjugated

ECT2 Polyclonal Antibody

E-AB-53424-200uL 200uL
EUR 399
Description: Unconjugated

ECT2 Polyclonal Antibody

E-AB-53424-20uL 20uL
EUR 73
Description: Unconjugated

ECT2 Polyclonal Antibody

E-AB-53424-60uL 60uL
EUR 143
Description: Unconjugated

ECT2 Antibody, HRP conjugated

1-CSB-PA888001LB01HU
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  • 100ug
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Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

ECT2 Antibody, FITC conjugated

1-CSB-PA888001LC01HU
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Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

OACD03154-1ML - ECT2 Antibody

OACD03154-1ML 1ml
EUR 669

OACD03155-1ML - ECT2 Antibody

OACD03155-1ML 1ml
EUR 669

ECT2 Antibody, Biotin conjugated

1-CSB-PA888001LD01HU
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  • 100ug
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Description: A polyclonal antibody against ECT2. Recognizes ECT2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Rabbit Polyclonal ECT2 Antibody

TA590497 100 µg Ask for price

OACD03154-100UL - ECT2 Antibody

OACD03154-100UL 100ul
EUR 199

OACD03155-100UL - ECT2 Antibody

OACD03155-100UL 100ul
EUR 199

ECT2 Mouse Monoclonal Antibody

E10G34303 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ECT2 Rabbit Polyclonal Antibody

E10G05742 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

ECT2 Rabbit Polyclonal Antibody

E10G12612 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Monoclonal ECT2 Antibody, Clone: 1691CT516.3.3

AMM02569G 0.1ml
EUR 580.8
Description: A Monoclonal antibody against Human ECT2. The antibodies are raised in Mouse and are from clone 1691CT516.3.3. This antibody is applicable in WB, E

OAAB11086-400UL - ECT2 Antibody - middle region

OAAB11086-400UL 400ul
EUR 389

OAGA01220-100UL - ECT2 Antibody - N-terminal region

OAGA01220-100UL 100ul
EUR 369

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx432637-200ul 200 ul
EUR 460.8

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx334431
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx104055
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

20-abx104056
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  • 100 ug
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  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx028279-400ul 400 ul
EUR 627.6

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx028279-80l 80 µl
EUR 343.2

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104055-100g 100 µg
EUR 750

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104055-20g 20 µg
EUR 275

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104055-50g 50 µg
EUR 337.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104056-100g 100 µg
EUR 750

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104056-20g 20 µg
EUR 275

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx104056-50g 50 µg
EUR 337.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx028279-400l 400 µl
EUR 518.75

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx432637-100g 100 µg
EUR 387.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx334431-100g 100 µg
EUR 362.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx334431-20g 20 µg
EUR 162.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody

abx334431-50g 50 µg
EUR 250

ECT2

E8ER1907-92 100ul
EUR 275
Description: Available in various conjugation types.

Monoclonal ECT2 monoclonal antibody (M01), Clone: 5D4

AMM04340G 0.1mg
EUR 580.8
Description: A Monoclonal antibody against Human ECT2 monoclonal (M01). The antibodies are raised in mouse and are from clone 5D4. This antibody is applicable in WB

Ect2 (untagged) - Mouse ect2 oncogene (Ect2), transcript variant 2, (10ug)

MC222366 10 µg Ask for price

Ect2 (untagged) - Mouse ect2 oncogene (Ect2), transcript variant 1, (10ug)

MC222574 10 µg Ask for price

Ect2 (untagged) - Mouse ect2 oncogene (Ect2), transcript variant 3, (10ug)

MC220714 10 µg Ask for price

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (HRP)

20-abx337249
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  • 100 ug
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Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (HRP)

abx337249-100g 100 µg
EUR 362.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (HRP)

abx337249-20g 20 µg
EUR 162.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (HRP)

abx337249-50g 50 µg
EUR 250

ECT2 (Center) rabbit polyclonal antibody, Aff - Purified

AP51360PU-N 400 µl Ask for price

Mouse Protein ECT2, Ect2 ELISA KIT

ELI-32217m 96 Tests
EUR 1038

Human Protein ECT2, ECT2 ELISA KIT

ELI-09348h 96 Tests
EUR 988.8

Human Protein ECT2 (ECT2) ELISA Kit

abx521509-96tests 96 tests
EUR 687.5

Mouse Protein ECT2 (ECT2) ELISA Kit

abx521510-96tests 96 tests
EUR 687.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (FITC)

20-abx337250
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  • 100 ug
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  • 200 ug
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Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (FITC)

abx337250-100g 100 µg
EUR 362.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (FITC)

abx337250-20g 20 µg
EUR 162.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (FITC)

abx337250-50g 50 µg
EUR 250

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

20-abx337251
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  • 100 ug
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  • 200 ug
  • 20 ug
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Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

20-abx272498
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  • 100 ug
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  • 1 mg
  • 200 ug
  • 50 ug

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

abx272498-1ml 1 ml
EUR 825

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

abx272498-200l 200 µl
EUR 362.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

abx337251-100g 100 µg
EUR 362.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

abx337251-20g 20 µg
EUR 162.5

Epithelial Cell Transforming Sequence 2 (ECT2) Antibody (Biotin)

abx337251-50g 50 µg
EUR 250

Ect2 (GFP-tagged) - Mouse ect2 oncogene (Ect2) transcript variant 1, (10ug)

MG223423 10 µg Ask for price

Ect2 (GFP-tagged) - Mouse ect2 oncogene (Ect2) transcript variant 2, (10ug)

MG224170 10 µg Ask for price

Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 2

MR224170 10 µg Ask for price

Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 1

MR223423 10 µg Ask for price

Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 3

MR211053 10 µg Ask for price

ECT2 (N-term) goat polyclonal antibody, Aff - Purified

AP16137PU-N 100 µg Ask for price

ECT2 siRNA

20-abx914934
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  • 15 nmol
  • 30 nmol

ECT2 siRNA

20-abx914935
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  • 15 nmol
  • 30 nmol

ECT2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)

TA807408 100 µl Ask for price

ECT2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)

TA807408S 30 µl Ask for price

ECT2 Peptide

45-517P 0.1 mg
EUR 405.6
Description: ECT2 Peptide

Rabbit polyclonal ECT2 phospho T790 antibody (Phospho-specific)

TA319414 100 µg Ask for price

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody

CAU24267-100ul 100ul
EUR 235.2

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody

CAU24267-200ul 200ul
EUR 294

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody

CAU24268-100ul 100ul
EUR 235.2

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody

CAU24268-200ul 200ul
EUR 294

Ect2 (untagged) - Rat epithelial cell transforming 2 (Ect2)

RN217314 10 µg Ask for price

Lenti ORF clone of Ect2 (mGFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 2

MR224170L4 10 µg Ask for price

Lenti ORF clone of Ect2 (mGFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 1

MR223423L4 10 µg Ask for price

Lenti ORF clone of Ect2 (mGFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 3

MR211053L4 10 µg Ask for price

Polyclonal Antibody to Epithelial Cell Transforming Sequence 2 (ECT2)

PAC451Hu01 100ul
EUR 245

Polyclonal Antibody to Epithelial Cell Transforming Sequence 2 (ECT2)

PAC451Hu02 100ul
EUR 245

ECT2 Mouse mAb

E2618275 100ul
EUR 225
Description: Available in various conjugation types.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human)

4-PAC451Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2)

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human)

4-PAC451Hu02
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2)

Lenti ORF clone of Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 2

MR224170L3 10 µg Ask for price

Lenti ORF clone of Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 1

MR223423L3 10 µg Ask for price

Lenti ORF clone of Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 3

MR211053L3 10 µg Ask for price

ECT2 Blocking Peptide

33R-4471 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ECT2 antibody, catalog no. 70R-5714

ECT2 Blocking Peptide

33R-7035 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ECT2 antibody, catalog no. 70R-5730

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), PE

4-PAC451Hu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with PE.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), PE

4-PAC451Hu02-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with PE.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC

4-PAC451Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Cy3

4-PAC451Hu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Cy3.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), FITC

4-PAC451Hu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with FITC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), HRP

4-PAC451Hu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with HRP.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC

4-PAC451Hu02-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Cy3

4-PAC451Hu02-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Cy3.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), FITC

4-PAC451Hu02-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with FITC.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), HRP

4-PAC451Hu02-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with HRP.

Ect2 (myc-DDK-tagged) - Rat epithelial cell transforming 2 (Ect2)

RR217314 10 µg Ask for price

ECT2 (untagged)-Human epithelial cell transforming sequence 2 oncogene (ECT2)

SC113779 10 µg Ask for price

ECT2 (untagged)-Human epithelial cell transforming sequence 2 oncogene (ECT2)

SC318356 10 µg Ask for price

Lenti ORF particles, Ect2 (GFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 2, 200ul, >10^7 TU/mL

MR224170L4V 200 µl Ask for price

Lenti ORF particles, Ect2 (GFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 1, 200ul, >10^7 TU/mL

MR223423L4V 200 µl Ask for price

Lenti ORF particles, Ect2 (GFP-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 3, 200ul, >10^7 TU/mL

MR211053L4V 200 µl Ask for price

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Biotinylated

4-PAC451Hu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Biotin.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), Biotinylated

4-PAC451Hu02-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with Biotin.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC-Cy7

4-PAC451Hu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC-Cy7.

Epithelial Cell Transforming Sequence 2 (ECT2) Polyclonal Antibody (Human), APC-Cy7

4-PAC451Hu02-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
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Description: A Rabbit polyclonal antibody against Human Epithelial Cell Transforming Sequence 2 (ECT2). This antibody is labeled with APC-Cy7.

Human ECT2 shRNA Plasmid

20-abx951320
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  • 150 µg
  • 300 µg

Mouse ECT2 shRNA Plasmid

20-abx970099
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  • 150 µg
  • 300 µg

Lenti ORF particles, Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 2, 200ul, >10^7 TU/mL

MR224170L3V 200 µl Ask for price

Lenti ORF particles, Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 1, 200ul, >10^7 TU/mL

MR223423L3V 200 µl Ask for price

Lenti ORF particles, Ect2 (Myc-DDK-tagged) - Mouse ect2 oncogene (Ect2), transcript variant 3, 200ul, >10^7 TU/mL

MR211053L3V 200 µl Ask for price

ECT2 (GFP-tagged) - Human epithelial cell transforming sequence 2 oncogene (ECT2)

RG211319 10 µg Ask for price

Ect2 (GFP-tagged) - Mouse ect2 oncogene (cDNA clone MGC:29128 IMAGE:5067358)

MG211053 10 µg Ask for price

ECT2 (Myc-DDK-tagged)-Human epithelial cell transforming sequence 2 oncogene (ECT2)

RC211319 10 µg Ask for price

ECT2 ORF Vector (Human) (pORF)

ORF018676 1.0 ug DNA
EUR 486

Ect2 ORF Vector (Mouse) (pORF)

ORF043598 1.0 ug DNA
EUR 607.2

Ect2 ORF Vector (Mouse) (pORF)

ORF043599 1.0 ug DNA
EUR 607.2

Ect2 ORF Vector (Mouse) (pORF)

ORF043600 1.0 ug DNA
EUR 607.2

Human ECT2 Protein Lysate 20ug

IHUECT2PLLY20UG each
EUR 213
Description: Human ECT2 Protein Lysate 20ug

Carrier-free (BSA/glycerol-free) ECT2 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9)

CF807408 100 µg Ask for price

OCOA09753-20UG - ECT2 Protein Lysate

OCOA09753-20UG 20ug
EUR 169

ECT2 Over-expression Lysate Product

GWB-C7A3D9 0.1 mg Ask for price

OPCD02842-10UG - ECT2 Recombinant Protein

OPCD02842-10UG 10ug
EUR 139

OPCD02842-50UG - ECT2 Recombinant Protein

OPCD02842-50UG 50ug
EUR 349

OPCD02843-10UG - ECT2 Recombinant Protein

OPCD02843-10UG 10ug
EUR 139

OPCD02843-50UG - ECT2 Recombinant Protein

OPCD02843-50UG 50ug
EUR 349

OPCD02842-200UG - ECT2 Recombinant Protein

OPCD02842-200UG 200ug
EUR 699

OPCD02843-200UG - ECT2 Recombinant Protein

OPCD02843-200UG 200ug
EUR 699

Case Report: Identification of a Novel Variant (m.8909T>C) of Human Mitochondrial ATP6 Gene and Its Practical Penalties on Yeast ATP Synthase

 With the arrival of subsequent era sequencing, the record of mitochondrial DNA (mtDNA) mutations recognized in sufferers quickly and constantly expands. They’re regularly present in a restricted quantity of circumstances, typically a single particular person (as with the case herein reported) and in heterogeneous genetic backgrounds (heteroplasmy), which makes it tough to conclude about their pathogenicity and useful penalties.

As an organism amenable to mitochondrial DNA manipulation, capable of survive by fermentation to loss-of-function mtDNA mutations, and the place heteroplasmy is unstable, Saccharomyces cerevisiae is an wonderful mannequin for investigating novel human mtDNA variants, in isolation and in a managed genetic context.

We herein report the identification of a novel variant in mitochondrial ATP6 gene, m.8909T>C. It was discovered together with the well-known pathogenic m.3243A>G mutation in mt-tRNALeu.

We present that an equal of the m.8909T>C mutation compromises yeast adenosine tri-phosphate (ATP) synthase meeting/stability and reduces the speed of mitochondrial ATP synthesis by 20-30% in comparison with wild sort yeast.

Different beforehand reported ATP6 mutations with well-established pathogenicity (like m.8993T>C and m.9176T>C) had been proven to have related results on yeast ATP synthase. It may be inferred that alone the m.8909T>C variant has the potential to compromise human well being.

Investigating the Position of Telomere and Telomerase Related Genes and Proteins in Endometrial Most cancers

  • Endometrial most cancers (EC) is the most typical gynaecological malignancy. Present prognostic markers are insufficient to precisely predict affected person survival, necessitating novel prognostic markers, to enhance remedy methods.
  • Telomerase has a novel function throughout the endometrium, while aberrant telomerase exercise is a trademark of many cancers.
  • The intention of the present in silico research is to research the function of telomere and telomerase related genes and proteins (TTAGPs) in EC to establish potential prognostic markers and therapeutic targets.
  • Evaluation of RNA-seq knowledge from The Most cancers Genome Atlas recognized differentially expressed genes (DEGs) in EC (568 TTAGPs out of 3467) and ascertained DEGs related to histological subtypes, greater grade endometrioid tumours and late stage EC.
  • Practical evaluation demonstrated that DEGs had been predominantly concerned in cell cycle regulation, whereas the survival evaluation recognized 69 DEGs related with prognosis. The protein-protein interplay community constructed facilitated the identification of hub genes, enriched transcription issue binding websites and medicines that will goal the community.
  • Thus, our in silico strategies distinguished many important genes related to telomere upkeep that had been beforehand unknown to contribute to EC carcinogenesis and prognosis, together with NOP56WFS1ANAPC4and TUBB4A. Probing the prognostic and therapeutic utility of those novel TTAGP markers will type an thrilling foundation for future analysis.

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