Expression adjustments of cytotoxicity and apoptosis genes in HTLV-1-associated myelopathy/tropical spastic paraparesis sufferers from the attitude of system virology
Though human T-cell lymphotropic virus type-1 (HTLV-1) was the primary retrovirus amongst human pathogens to be recognized, inadequate data on the pathogenesis of HTLV-1 an infection implies that no exact mechanism has but been offered for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Primarily based on earlier research, it was discovered that apoptosis and irritation stimulation have been among the many most vital mechanisms underlying HAM/TSP. The current examine offers an in-silico evaluation of the microarray knowledge associated to HAM/TSP sufferers. Expression adjustments of the genes accountable for cytotoxicity and apoptosis processes of HAM/TSP sufferers and asymptomatic carriers have been investigated.
Expression of the genes concerned in cytotoxicity and apoptosis in HAM/TSP sufferers was decreased; therefore, a mannequin was proposed indicating that the unfold of immune responses in HAM/TSP could also be on account of expression of HTLV-1 virulence components and the resistance of HTLV-1-infected cells to apoptosis.
Genetic variations in autoimmune genes and VKH illness
Goal: Vogt-Koyanagi-Harada (VKH) illness is a uncommon autoimmune illness. The autoimmune response in VKH illness is towards the melanin-producing cells; due to this fact, in affected people melanocyte-containing organs manifest illness signs together with eyes, ears, pores and skin and nervous system. VKH is a multifactorial illness, and the exact reason for the VKH illness is unknown. Research have prompt that each environmental and genetic components are accountable for the VKH illness. On this evaluate, the authors have collected all of the obtainable literature on the genetics of VKH to their data and mentioned the function of genetic variants in inflicting VKH illness.
Strategies: An in depth literature search was carried out with a purpose to evaluate all of the revealed research relating to VKH medical phenotyping and genetic variants in VKH illness. Medline, PubMed, Cochrane library, and Scopus was searched utilizing mixture of key phrases.
Outcomes: It was discovered that variants in HLA genes, IL-12b, TNFSF4, and miR-20-5p genes are considerably related to VKH; nevertheless, variants in genes ATG10, TNIP1 and CLEC16A didn’t obtain important genome-wide affiliation threshold. Furthermore, polymorphisms in TNIP1 and CLEC16A play a protecting function towards VKH.
Conclusion: The authors conclude that elevated pattern measurement and a extra homogeneous VKH affected person inhabitants could reveal a major affiliation of variants in ATG10, TNIP1 and CLEC16A genes with VKH illness.
Description: Qualitativeindirect ELISA kit for measuring Human T-lymphotropicvirusâ… /II (HTLV-â… /II) antibody in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human T-lymphotropicvirusâ… /II(HTLV-â… /II) antibody ELISA kit
Description: Qualitativeindirect ELISA kit for measuring Human T-lymphotropicvirusâ… /II(HTLV-â… /II) antibody in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: A competitive ELISA for quantitative measurement of Canine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Canine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Canine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Porcine S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human T-Lymphotropic Virus 1+2 (HTLV-1/2) ELISA Kit
Description: A competitive ELISA for quantitative measurement of Goat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Goat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Goat S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Mouse S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Human S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Rabbit S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A competitive ELISA for quantitative measurement of Monkey S Antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Characterization of PcLEA14, a Group 5 Late Embryogenesis Plentiful Protein Gene from Pear ( Pyruscommunis)
Fruit timber want to beat harsh winter climates to make sure perennially; due to this fact, they’re strongly influenced by environmental stress. Within the current examine, we centered on the pear homolog PcLEA14 belonging to the distinctive 5C late embryogenesis ample (LEA) protein group for which data is restricted on fruit timber. PcLEA14 was confirmed to belong to this protein group utilizing phylogenetic tree evaluation, and its expression was induced by low-temperature stress. The seasonal fluctuation in its expression was thought of to be associated to its function in enduring overwinter temperatures, which is especially vital in perennially.
Furthermore, the perform of PcLEA14 in low-temperature stress tolerance was revealed in transgenic Arabidopsis. Subsequently, the pear homolog of dehydration-responsive element-binding protein/C-repeat binding factor1 (DREB1), which is a crucial transcription think about low-temperature stress tolerance and is uncharacterized in pear, was analyzed after bioinformatics evaluation revealed the presence of DREB cis-regulatory components in PcLEA14 and the dormancy-related gene, each of that are additionally expressed throughout low temperatures.
Among the many 5 PcDREBs, PcDREB1A and PcDREB1C exhibited related expression patterns to PcLEA14 whereas the opposite PcDREBs weren’t expressed in winter, suggesting their completely differentphysiological roles. Our findings counsel that the low-temperature tolerance mechanism in overwintering timber is related to group 5C LEA proteins and DREB1.
A job for microRNAs within the epigenetic management of sexually dimorphic gene expression within the human placenta
Goal: The contribution of miRNAs as epigenetic regulators of sexually dimorphic gene expression within the placenta is unknown.
Supplies & strategies: 382 placentas from the extraordinarily low gestational age newborns (ELGAN) cohort have been evaluated for expression ranges of 37,268 mRNAs and a couple of,102 miRNAs utilizing genome-wide RNA-sequencing. Differential expression evaluation was used to establish variations within the expression based mostly on the intercourse of the fetus.
Outcomes: Sexually dimorphic expression was noticed for 128 mRNAs and 59 miRNAs. A set of 25 miRNA grasp regulators was recognized that possible contribute to the sexual dimorphic mRNA expression.
Conclusion: These knowledge spotlight sex-dependent miRNA and mRNA patterning within the placenta and supply perception into a possible mechanism for noticed intercourse variations in outcomes.
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000
Description: A polyclonal antibody against FYN. Recognizes FYN from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/10000
Description: A polyclonal antibody against FYN. Recognizes FYN from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000
Description: FYN is a non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance.
Description: FYN is a non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance.
Description: FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.
Description: FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.
Description: Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Description: Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Description: Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta- catenin). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT. Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage. Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL and TRPC6. Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein. Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation. Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts. CSK maintains LCK and FYN in an inactive form. Promotes CD28-induced phosphorylation of VAV1.
Description: Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through phosphorylation of CTNNB1 (beta-catenin) and CTNND1 (delta- catenin). Regulates cytoskeletal remodeling by phosphorylating several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT. Promotes cell survival by phosphorylating AGAP2/PIKE-A and preventing its apoptotic cleavage. Participates in signal transduction pathways that regulate the integrity of the glomerular slit diaphragm (an essential part of the glomerular filter of the kidney) by phosphorylating several slit diaphragm components including NPHS1, KIRREL and TRPC6. Plays a role in neural processes by phosphorylating DPYSL2, a multifunctional adapter protein within the central nervous system, ARHGAP32, a regulator for Rho family GTPases implicated in various neural functions, and SNCA, a small pre-synaptic protein. Participates in the downstream signaling pathways that lead to T-cell differentiation and proliferation following T-cell receptor (TCR) stimulation. Also participates in negative feedback regulation of TCR signaling through phosphorylation of PAG1, thereby promoting interaction between PAG1 and CSK and recruitment of CSK to lipid rafts. CSK maintains LCK and FYN in an inactive form. Promotes CD28-induced phosphorylation of VAV1.
Description: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [RefSeq]
Description: A Monoclonal antibody against Human SYN / FYN (aa7-176, clone FYN-59). The antibodies are raised in Mouse and are from clone FYN-59. This antibody is applicable in WB and IHC-P, IP
Monoclonal SYN / FYN Antibody (aa7-176, clone FYN-01), Clone: FYN-01
Description: A Monoclonal antibody against Human SYN / FYN (aa7-176, clone FYN-01). The antibodies are raised in Mouse and are from clone FYN-01. This antibody is applicable in WB and IHC-P, ICC, IP
Description: A polyclonal antibody against FYN. Recognizes FYN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody against FYN. Recognizes FYN from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y530
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213
Description: A polyclonal antibody for detection of Fyn from Human, Mouse, Rat. This Fyn antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the non-phosphorylation site of Y213
Description: A polyclonal antibody against FYN (Ab-530). Recognizes FYN (Ab-530) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000
Description: A polyclonal antibody against FYN (Ab-530). Recognizes FYN (Ab-530) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000
Description: A Monoclonal antibody against Human FYN. The antibodies are raised in Mouse and are from clone 2A10. This antibody is applicable in WB and IHC, FC, ICC, E
Description: A Monoclonal antibody against Human FYN. The antibodies are raised in Mouse and are from clone 1302CT390.118.237. This antibody is applicable in WB, FC, IHC-P, E
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is unconjugated.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to APC .
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Biotin.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to FITC.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to HRP.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to PerCP.
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to RPE .
Description: A polyclonal antibody for Fyn (pTyr530) from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human Fyn around the phosphorylation site of tyrosine 530 (pTyr530).. The Antibody is tested and validated for WB, IHC, ELISA assays with the following recommended dilutions: WB (1:250-1:500); IHC (1:25-1:50); ELISA (1:1000). This Fyn (pTyr530) antibody is conjugated to Streptavidin.
Description: Fyn-related kinase (Frk) is a tyrosine kinase of the Src family. Also known as Rak, Gtk, and Iyk, Frk is predominantly expressed in epithelial tissues. Frk protein is 49% and 47% identical to Fyn and Csk, respectively. Src family kinases regulate an array of cellular processes, including growth factor signaling, cytoskeleton dynamics, and cell proliferation.
Description: A polyclonal antibody for detection of Fyn phospho Tyr530) from Human, Mouse, Rat. This Fyn phospho Tyr530) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the phosphorylation site of Y530
Description: A polyclonal antibody for detection of Fyn phospho Tyr530) from Human, Mouse, Rat. This Fyn phospho Tyr530) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the phosphorylation site of Y530
Description: A polyclonal antibody for detection of Fyn phospho Tyr530) from Human, Mouse, Rat. This Fyn phospho Tyr530) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Fyn around the phosphorylation site of Y530
Description: A Rabbit Polyclonal antibody against Fyn (phospho Tyr530) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
Description: A Rabbit Polyclonal antibody against Fyn (phospho Tyr530) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
FYN Oncogene Related To SRC/FGR/YES Phospho-Tyr530 (FYN pY530) Antibody
Description: A Monoclonal antibody against Human SYN / FYN (clone 2A10). The antibodies are raised in Mouse and are from clone 2A10. This antibody is applicable in WB and IHC-P, IF, ICC, E, Flo
Description: Embryonal Fyn-associated substrate is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).
Description: Embryonal Fyn-associated substrate is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).
Description: Fyn is a protein encoded by the FYN gene which is approximately 60,7 kDa. Fyn is localised to the cytoplasm, cell membrane and nucleus. It is involved in RET signalling, GAB1 signalosome, EPH-Ephrin signalling, HIV life cycle and the development Slit-Robo signalling. It is a membrane-associated tyrosine kinase that plays a role in the regulation of cell growth and survival, cell adhesion, integrin-mediated signalling, cytoskeletal remodelling, cell motility, immune response and axon guidance. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Fyn isoform 1 is highly expressed in the brain and isoform 2 is expressed in cells of hemopoietic lineages, especially T-lymphocytes. Mutations in the FYN gene may result in Wiskott-Aldrich syndrome. STJ93171 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Fyn protein.
